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23andMe, IBM and now uBiome is the next tech company to jump into the lucrative multi-billion dollar drug discovery market.
The company started out with a consumer gut health test to check whether your intestines carry the right kind of bacteria for healthy digestion but has since expanded to include over 250,000 samples for everything from the microbes on your skin to vaginal health — the largest data set in the world for these types of samples, according to the company.
Founder Jessica Richman now says there’s a wider opportunity to use this data to create value in therapeutics.
To support its new drug discovery efforts, the San Francisco-based startup will be moving its therapeutics unit into new Cambridge, Massachusetts headquarters and appointing former Novartis CEO Joseph Jimenez to the board of directors as well.
The company has a healthy pile of cash to help build out that new HQ, too, with a fresh $83 million Series C, lead by OS Fund and in participation with 8VC, Y Combinator, Dentsu Ventures and others.
The drug discovery market is slated to be worth nearly $86 billion by 2022, according to BCC Research numbers. New technologies — those that solve logistics issues and shorten the time between research and getting a drug to market in particular — are driving the growth and that’s where uBiome thinks it can get into the game.
“This financing allows us to expand our product portfolio, increase our focus on patent assets and further raise our clinical profile, especially as we begin to focus on commercialization of drug discovery and development of our patent assets,” Richman said.
Though its unclear at this time which drug maker the company might partner up with, Richman did say there would be plenty to announce later on that front.
So far, the company has published over 30 peer-reviewed papers on microbiome research, has entered into research partnerships with the likes of the Center for Disease Control (CDC) and leading research institutions such as Harvard, MIT and Stanford and has previously raised $22 million in funding. The additional VC cash puts the total amount raised to $105 million to date.
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In a world where nothing can be trusted and fake news abounds, ICO and crypto teams are further muddying the waters by trying – and often failing – to pay for posts. While bribes for blogs is nothing new, sadly the current crop of ICO creators and crypto projects are particularly interested in scaling fast and many ICO CEOs are far happier with scammy multi-level marketing tricks than real media relations.
The worst part of this spammy, scammy ecosystem is the service providers. A new group of media organizations are appearing where pay-to-post is the norm rather than the rare exception. I’ve been looking at these groups for a while now and recently found a few egregious examples.
But first some background.
Say you’re trying to publicize a startup. You’ve emailed all the big names in the industry and the emails have gone unanswered. Your product is about to flounder on the market without users and you can’t get any because, in perfect chicken-or-egg fashion, you can’t get funding without users and you can’t get users without funding. So isn’t it a good idea to pay a few dollars for a little press?
No.
And isn’t most PR just pay-for-post anyway?
No.
PR people are consummate networkers and are paid to reach out to media on your behalf and their particular set of skills, honed over long careers, are dedicated to breaking down the forcefield between the journalist and the outside world. They are your surrogate hustlers, dedicated to getting you more exposure. A good PR person is worth their weight in gold. They can call up a popular journalist and make a simple pitch: “This cool new thing is happening. Can I put you in touch?”
If a journalist’s mission is to afflict the comfortable and comfort the afflicted, a good PR person makes the comfortable look slightly afflicted in order to give the journalist a better story. Also, like velociraptors, they are tenacious and will follow up multiple times on your behalf.
A bad PR person, on the other hand, will cold-call hundreds of journalists and read a script that is half the length of Moby Dick. They produce little more than spam and their efforts begin and end with pressing the “Send” button. It’s also interesting to note that many bad PR people, of late, have found new life as ICO specialists.
Now meet the pay-for-post hucksters. As I wrote before, there is now a subset of the PR world that offers to get your press release or story on the top of various websites for the low, low price of between $500 and $13,000. For example, one set of hucksters created a small business selling posts on Harvard.edu by creating garbage WordPress blogs and posting press releases to increase SEO coverage. Further, I received a document that outlined the prices for placement in various blogs including this one. While it is impossible to buy a post on TechCrunch this way, it doesn’t stop many from trying.

What’s the difference between that price list and the job a PR person will do for you? The difference is trust. A pay-for-post huckster is dependent on convincing poorly paid freelance writers to add links and other dross to their posts in order to get a “placement.” I get requests like this almost every day and almost all the journalists I talked to reported the same.

Some entrepreneurs are savvy enough to avoid these scams. Even more aren’t.
“I’ve never paid since I think it’s almost always a waste of money but I’ve been offered this type of coverage many times,” said Rick Ramos, of HealthJoy.com. “The last offer was for Kathy Ireland’s Worldwide Business… A TV show that I’ve never heard of in my life. I’ve also been approached by niche publications like InsuranceOutlook and HealthCareTechOutlook that want $3,000 for a ‘reprint branding package.’ A quick Alexa.com search shows their rank as 1,725,207 and 1,054,501 globally. I think I get pitched at least every six months for one of these types of packages.
Unfortunately, many of these organizations hide their request for payment until the last minute. That said, how do you know when it’s someone selling pay-for-play vs. a real editor? It’s usually obvious.
“It’s usually pretty easy to sniff out based on their email blast. It’s pretty untargeted with no reference to what your company does or how it related to a story. Some people are up front about the payment but others want a ’15 min call to discuss.’ A quick LinkedIn search always shows them as a sales person versus a reporter or editor,” said Ramos.
This is a document I received from a company attempting an ICO. This sort of menu was quite uncommon until fairly recently when the “on-demand” economy melded with PR scammers. The completeness of the document is unique – you could feasibly plan your own PR efforts just by reaching out to journalists who work at all of these places. But you’ll also note that each spot has its own price, often in the low hundreds of dollars, which means that those spots are mostly pay-for-play anyway.
ICOLists by on Scribd
No PR company can promise coverage. In fact, many pay-for-play folks mention this in their communications, hiding it in plain sight. This snippet of text appeared in a contract for work from one of the pay-for-play providers. In short, you’re paying for something they cannot guarantee to get. Interestingly, the PR company below calls their product an IO – an insertion order – which is language used in ad sales. Further, they take great pains in explaining that it is almost impossible to achieve what they promise.

None of the pay-for-post folks I mentioned here would respond to my requests for comment.

Journalists should never expect money for coverage.
Yet many do.
“Lately I have worked on a number of blockchain technology pieces and I have encountered a wide variety of these asks,” said Brittany Whitmore, CEO at Exvera Communications. “A lot of the new, smaller blockchain-focused outlets seem to do a lot of pay-to-play, likely trying to capitalize on the ICO gold rush. The strangest request that I received was that the outlet would do a an article about the news for free but only if we paid them over $1,000 to promote the article with ads. I did not proceed.”
In one very detailed article on The Outline, Jon Christian explored this world and found that many writers received small sums for a single brand mention in a story, a sort of SEO flogging that rarely helps. He wrote:
An unpaid contributor to the Huffington Post, also speaking on condition of anonymity because, in his words, “I would be pretty fucked if my name got out there,” said that he has included sponsored references to brands in his articles for years, in articles on the Huffington Post and other sites, on behalf of six separate agencies. Some agencies pay him directly, he said, in amounts that can be as small as $50 or $175, but others pay him through an employee’s personal PayPal account in order to obfuscate the source of the funds. In a statement, Huffington Post said “Using the HuffPost Contributors Network to self-publish paid content violates our terms of use. Anyone we discover to be engaging in such abuse has their post removed from the site and is banned from future publication.”
The Huffington Post writer also described specific brands he’d written about on behalf of one of the agencies, which ranged from a popular ride-hailing app, to a publicly-traded site for booking flights and hotels, to a large American cell phone service provider.
“This is a classic example of payola,” he said of the brand mentions, invoking a term that’s been used to describe radio DJs who accept payments from record companies in order to play certain artists on the air.
Further, many influencers – folks who sell their Internet fame to the highest bidder – masquerade as journalists, asking for outrageous sums to flog an ICO on their YouTube channel or Instagram page. Pay-for-play services can also put out organic content like this in hopes of appearing in the news.

The rule of thumb? Paid posts and native advertising are not journalism. Ultimately, journalists who charge for coverage are marketers. No one at any reputable news organization will ask for cash but, sadly, there are a number of disreputable news organizations making the rounds.

All this still doesn’t answer the question: Should you pay-to-post?
“The short answer is no,” said Kevin Bourke of BourkePR. “I get asked all the time, and in fact, turned down another request just today. And I advise my clients to decline these offers as well.”
Pay-for-post disrupts journalism in a way that should be familiar and desirable to any modern-day entrepreneur. Middlemen are being knocked out everywhere and brands are approaching consumers from every angle including native ads in Instagram and Twitter. But the value of coverage – real coverage – from a journalists perspective is the opportunity to explain complex ideas to a ready audience. While posting a picture of a blockchain on Facebook and hoping for clicks is one strategy, explaining your views, opinions, and insights is far more important even if you approach it from a mercenary position.
“When you start paying for placement, you remove objectivity and credibility, and in my opinion, this is the reason you look for coverage of your company/products in the first place. That’s what influences readers/viewers. But I understand the temptation for startups. You come to believe that ‘all visibility is good visibility.’ I just can’t agree with that,” said Bourke. “I see the trend toward paid placements (now called sponsored content), paid awards and I can’t stand it – especially with the trade show awards in high tech. They’ve completely devalued the Best of Show awards in so many cases. Typically, only the big companies with budgets can afford them, so many of the smaller guys with no money but amazing products get left out. I understand that the publishing industry needs to figure out new revenue streams – these are very difficult times for them. But they need to figure out smarter business models and maintain the integrity of editorialized content, built on the opinions and perspectives of journalists and influencers.”
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CEOs of funded startups tend to be a well-educated bunch, at least when it comes to university degrees.
Yes, it’s true college dropouts like Mark Zuckerberg and Bill Gates can still do well. But Crunchbase data shows that most startup chief executives have an advanced degree, commonly from a well-known and prestigious university.
Earlier this month, Crunchbase News looked at U.S. universities with strong track records for graduating future CEOs of funded companies. This unearthed some findings that, while interesting, were not especially surprising. Stanford and Harvard topped the list, and graduates of top-ranked business schools were particularly well-represented.
In this next installment of our CEO series, we narrowed the data set. Specifically, we looked at CEOs of U.S. companies funded in the past three years that have raised at least $100 million in total venture financing. Our intent was to see whether educational backgrounds of unicorn and near-unicorn leaders differ markedly from the broad startup CEO population.
Here’s the broad takeaway of our analysis: Most CEOs of well-funded startups do have degrees from prestigious universities, and there are a lot of Harvard and Stanford grads. However, chief executives of the companies in our current data set are, educationally speaking, a pretty diverse bunch with degrees from multiple continents and all regions of the U.S.
In total, our data set includes 193 private U.S. companies that raised $100 million or more and closed a VC round in the past three years. In the chart below, we look at the universities most commonly attended by their CEOs:1

The rankings aren’t hugely different from the broader population of funded U.S. startups. In that data set, we also found Harvard and Stanford vying for the top slots, followed mostly by Ivy League schools and major research universities.
For heavily funded startups, we also found a high proportion of business school degrees. All of the University of Pennsylvania alum on the list attended its Wharton School of Business. More than half of Harvard-affiliated grads attended its business school. MBAs were a popular credential among other schools on the list that offer the degree.
When it comes to the most heavily funded startups, the degree mix gets quirkier. That makes sense, given that we looked at just 20 companies.
In the chart below, we look at alumni affiliations for CEOs of these companies, all of which have raised hundreds of millions or billions in venture and growth financing:

One surprise finding from the U.S. startup data set was the prevalence of Canadian university grads. Three CEOs on the list are alums of the University of Waterloo . Others attended multiple well-known universities. The list also offers fresh proof that it’s not necessary to graduate from college to raise billions. WeWork CEO Adam Neumann just finished his degree last year, 15 years after he started. That didn’t stop the co-working giant from securing more than $7 billion in venture and growth financing.
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Just swallow a pill and it expands into a balloon in your stomach so you don’t feel hungry. No gastric bypass, no surgery required. Sounds magical, but Boston-based Allurion has created the only non-invasive gastric balloon for obesity. Gastric balloons are nothing new, but you usually need anesthesia and a doctor to insert them. That makes the whole process expensive and prohibitive… Read More
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A seventeenth-century university has become the victim of a twenty-first-century crime. Harvard University on Wednesday announced that on June 19, it discovered a breach in the IT systems of its Faculty of Arts and Sciences and Central Administration, currently impacting eight different schools and administrative organizations at the university. A copy of the memo from Anne Margulies, VP… Read More
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While popular location-based social app Yik Yak struggles amid controversy and on-campus bannings, a newcomer called Spayce is gearing up to compete with its own take on local social networking. Its few-weeks-old app forgoes anonymity by default, and instead encourages community members to share their photo and video “memories” happening around a given location, whether that’s… Read More
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