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Longevity startup Longevica plans to launch supplements based on long-term research
A biotech company that has spent 11 years researching supplements to increase human longevity plans to launch its supplements later this year. Longevica says it has attracted a total of $13 million from investors, including Alexander Chikunov, a longevity investor, who is also president of the company.
Longevica says it created a biotechnology platform for longevity after researching the life-span of laboratory mice. It now aims to produce medicines, dietary supplements and food products.
The longevity space is a growing sector for tech startups. Google backed the launch of Calico in the space. Late last year Humanity Inc. raised $2.5 million in a round led by Boston fund One Way Ventures for its longevity company that will leverage AI to maximize people’s health span.
Longevica’s CEO Aynar Abdrakhmanov, backing up his company’s aim to tap the desire for people to live longer, said: “According to the WHO, by 2050, 2 billion people will be 60+ years old. By 2026, the sales of services and products for this audience will be around $27 trillion… By comparison, it was only $17 trillion in 2019.”
According to CB Insights, life-extension startups raised a record total of $800 million in 2018 alone. And there are some high-profile investors in the space.
PayPal co-founder Peter Thiel invested in Unity Biotechnology, which is developing drugs to treat diseases that accompany aging. And Ethereum founder Vitalik Buterin invested $2.4 million worth of Ether into the nonprofit SENS Research foundation, where famed longevity research Aubrey de Grey is chief science officer, to develop rejuvenation biotechnologies.
Longevica is basing its platform on the work of scientist Alexey Ryazanov, who holds 10 U.S. patents in the space, and is a longtime researcher into the regulation of protein biosynthesis cells.
Chikunov said: “I gathered scientists known in this field to discuss their approaches to the problem. Then Alexey Ryazanov proposed the innovative idea of large-scale screening of all known pharmacological substances on long-lived mice in order to find those that prolong life.”
Under the leadership of Ryazanov, Longevica says it used 20,000 long-lived female mice and 1,033 drugs representing compounds from 62 pharmacological classes to find five substances that statistically significantly increased longevity by 16-22%: Inulin, Pentetic Acid, Clofibrate, Proscillaridin A, D-Valine.
From this work, they formed a view about the elimination of certain heavy metals from the body and improved the body’s ability to remove toxins.
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Startups are transforming global trade in the COVID-19 era
Scott Bade is a former speechwriter for Mike Bloomberg and co-author of “More Human: Designing a World Where People Come First.”
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Global trade watchers breathed a sigh of relief on January 15, 2020.
After two years of threats, tariffs and tweets, there was finally a truce in the trade war between the U.S. and China. The agreement signed by President Trump and Chinese Vice Premier Liu He in the Oval Office didn’t resolve all trade tensions and maintained most of the $360 billion in tariffs the administration had put on Chinese goods. But for the first time in months, it looked like manufacturers, importers and shippers could start to put two difficult years behind them.
Then came COVID-19, at first a local disruption in Wuhan, China. Then it spread throughout Hubei province, causing havoc in a concentric circle that eventually engulfed the rest of China, where industrial production fell by more than 13.5% in the first two months of the year. When the virus spread everywhere, chaos ensued: Factories shuttered. Borders closed. Supply chains crumbled.
“It has had a cascading effect through the entire world’s economy,” says Anja Manuel, co-founder and managing partner of Rice, Hadley, Gates & Manuel LLC, an international strategic consulting firm based in Silicon Valley.
The crisis has caused a drastic contraction in global trade; the World Trade Organization estimates trade volumes will fall 13-20% in 2020. And spinning activity back up could be tricky: Even as China starts to get back online, the slowdown there could reduce worldwide exports by $50 billion this year. When factories do reopen, there’s no guarantee whether they will have parts available or empty warehouses, says Manuel, who also serves on the advisory board of Flexport, a shipping logistics startup. “Our supply chains are so tightly-knit and so just-in-time that throw a few wrenches in it like we’ve just done, and it’s going to be really hard to stand it back up again. The idea that we go back to normal the moment we lift restrictions is unlikely, fanciful, even.”
Getting to that new normal, though, is a job that a number of logistics startups are embracing. Already on the rise, companies like Flexport, Haven and Factiv see a global trade crisis as a setback, but also an opportunity to demonstrate the value of their digital platforms in a very much analog industry.
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The changing face of employment law during a global pandemic
Prompted by Jeff Bezos’s plans to test all Amazon employees for the virus that causes COVID-19, we wondered whether employers can mandate employee testing, regardless of symptoms. The issue pits public safety against personal privacy, but limited testing availability has rendered the question somewhat moot.
But as the World Health Organization and U.S. Centers for Disease Control and Prevention have noted, asymptomatic COVID-19 carriers can spread the virus without realizing they’re infected. To learn more about workers’ rights in this arena, we spoke to Tricia Bozyk Sherno, counsel at Debevoise & Plimpton, who focuses on employment and general commercial litigation.
The answer, for now, is not entirely straightforward, though updates from the U.S. Equal Employment Opportunity Commission could make the situation clearer going forward as more tests are made available and state governments begin pushing to reopen businesses.
Sherno offered a fair amount of insight into the EEOC’s updated guidance and made some predictions about how things may look for both employers and workers going forward.
TechCrunch: Prior to the COVID-19 pandemic, what sorts of laws governed an employer’s ability to test employees for infectious diseases?
Tricia Bozyk Sherno: Covered employers (employers with 15 or more employees) must comply with the requirements of the Americans with Disabilities Act (ADA), which limits an employer’s ability to make disability-related inquiries or require medical examinations. (Note that certain states may also have similar statutes in place.) Generally, disability-related inquiries and medical examinations are prohibited by the ADA except in limited circumstances. A “medical examination” is a procedure or test that seeks information about an individual’s physical or mental impairments or health — so infectious disease testing would fall into this category.
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Estimote launches wearables for workplace-level contact tracing for COVID-19
Bluetooth location beacon startup Estimote has adapted its technological expertise to develop a new product designed specifically for curbing the spread of COVID-19. The company created a new range of wearable devices that co-founder Steve Cheney believes can enhance workplace safety for those who have to be co-located at a physical workplace even while social distancing and physical isolation measures are in place.
The devices, called simply the “Proof of Health” wearables, aim to provide contact tracing — in other words, monitoring the potential spread of the coronavirus from person-to-person — at the level of a local workplace facility. The intention is to give employers a way to hopefully maintain a pulse on any possible transmission among their workforces and provide them with the ability to hopefully curtail any local spread before it becomes an outsized risk.
The hardware includes passive GPS location tracking, as well as proximity sensors powered by Bluetooth and ultra-wide-band radio connectivity, a rechargeable battery and built-in LTE. It also includes a manual control to change a wearer’s health status, recording states like certified health, symptomatic and verified infected. When a user updates their state to indicate possible or verified infection, that updates others they’ve been in contact with based on proximity and location-data history. This information is also stored in a health dashboard that provides detailed logs of possible contacts for centralized management. That’s designed for internal use within an organization for now, but Cheney tells me he’s working now to see if there might be a way to collaborate with WHO or other external health organizations to potentially leverage the information for tracing across enterprises and populations, too.
These are intended to come in a number of different form factors: the pebble-like version that exists today, which can be clipped to a lanyard for wearing and displaying around a person’s neck; a wrist-worn version with an integrated adjustable strap; and a card format that’s more compact for carrying and could work alongside traditional security badges often used for facility access control. The pebble-like design is already in production and 2,000 will be deployed now, with a plan to ramp production for as many as 10,000 more in the near future using the company’s Poland-based manufacturing resources.
Estimote has been building programmable sensor tech for enterprises for nearly a decade and has worked with large global companies, including Apple and Amazon . Cheney tells me that he quickly recognized the need for the application of this technology to the unique problems presented by the pandemic, but Estimote was already 18 months into developing it for other uses, including in hospitality industries for employee safety/panic button deployment.
“This stack has been in full production for 18 months,” he said via message. “We can program all wearables remotely (they’re LTE connected). Say a factory deploys this — we write an app to the wearable remotely. This is programmable IoT.
“Who knew the virus would require proof of health vis-a-vis location diagnostics tech,” he added.
Many have proposed technology-based solutions for contact tracing, including leveraging existing data gathered by smartphones and consumer applications to chart transmission. But those efforts also have considerable privacy implications, and require use of a smartphone — something Cheney says isn’t really viable for accurate workplace tracking in high-traffic environments. By creating a dedicated wearable, Cheney says that Estimote can help employers avoid doing something “invasive” with their workforce, since it’s instead tied to a fit-for-purpose device with data shared only with their employers, and it’s in a form factor they can remove and have some control over. Mobile devices also can’t do nearly as fine-grained tracking with indoor environments as dedicated hardware can manage, he says.
And contact tracing at this hyperlocal level won’t necessarily just provide employers with early warning signs for curbing the spread earlier and more thoroughly than they would otherwise. In fact, larger-scale contact tracing fed by sensor data could inform new and improved strategies for COVID-19 response.
“Typically, contact tracing relies on the memory of individuals, or some high-level assumptions (for example, the shift someone worked),” said Brianna Vechhio-Pagán of John Hopkins University’s Applied Physics Lab via a statement. “New technologies can now track interactions within a transmissible, or ~6-foot range, thus reducing the error introduced by other methods. By combining very dense contact tracing data from Bluetooth and UWB signals with information about infection status and symptoms, we may discover new and improved ways to keep patients and staff safe.”
With the ultimate duration of measures like physical distancing essentially up-in-the-air, and some predictions indicating they’ll continue for many months, even if they vary in terms of severity, solutions like Estimote’s could become essential to keeping essential services and businesses operating while also doing the utmost to protect the health and safety of the workers incurring those risks. More far-reaching measures might be needed, too, including general-public-connected, contact-tracing programs, and efforts like this one should help inform the design and development of those.
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An EU coalition of techies is backing a ‘privacy-preserving’ standard for COVID-19 contacts tracing
A European coalition of techies and scientists drawn from at least eight countries, and led by Germany’s Fraunhofer Heinrich Hertz Institute for telecoms (HHI), is working on contacts-tracing proximity technology for COVID-19 that’s designed to comply with the region’s strict privacy rules — officially unveiling the effort today.
China-style individual-level location-tracking of people by states via their smartphones even for a public health purpose is hard to imagine in Europe — which has a long history of legal protection for individual privacy. However the coronavirus pandemic is applying pressure to the region’s data protection model, as governments turn to data and mobile technologies to seek help with tracking the spread of the virus, supporting their public health response and mitigating wider social and economic impacts.
Scores of apps are popping up across Europe aimed at attacking coronavirus from different angles. European privacy not-for-profit, noyb, is keeping an updated list of approaches, both led by governments and private sector projects, to use personal data to combat SARS-CoV-2 — with examples so far including contacts tracing, lockdown or quarantine enforcement and COVID-19 self-assessment.
The efficacy of such apps is unclear — but the demand for tech and data to fuel such efforts is coming from all over the place.
In the UK the government has been quick to call in tech giants, including Google, Microsoft and Palantir, to help the National Health Service determine where resources need to be sent during the pandemic. While the European Commission has been leaning on regional telcos to hand over user location data to carry out coronavirus tracking — albeit in aggregated and anonymized form.
The newly unveiled Pan-European Privacy-Preserving Proximity Tracing (PEPP-PT) project is a response to the coronavirus pandemic generating a huge spike in demand for citizens’ data that’s intended to offer not just an another app — but what’s described as “a fully privacy-preserving approach” to COVID-19 contacts tracing.
The core idea is to leverage smartphone technology to help disrupt the next wave of infections by notifying individuals who have come into close contact with an infected person — via the proxy of their smartphones having been near enough to carry out a Bluetooth handshake. So far so standard. But the coalition behind the effort wants to steer developments in such a way that the EU response to COVID-19 doesn’t drift towards China-style state surveillance of citizens.
While, for the moment, strict quarantine measures remain in place across much of Europe there may be less imperative for governments to rip up the best practice rulebook to intrude on citizens’ privacy, given the majority of people are locked down at home. But the looming question is what happens when restrictions on daily life are lifted?
Contacts tracing — as a way to offer a chance for interventions that can break any new infection chains — is being touted as a key component of preventing a second wave of coronavirus infections by some, with examples such as Singapore’s TraceTogether app being eyed up by regional lawmakers.
Singapore does appear to have had some success in keeping a second wave of infections from turning into a major outbreak, via an aggressive testing and contacts-tracing regime. But what a small island city-state with a population of less than 6M can do vs a trading bloc of 27 different nations whose collective population exceeds 500M doesn’t necessarily seem immediately comparable.
Europe isn’t going to have a single coronavirus tracing app. It’s already got a patchwork. Hence the people behind PEPP-PT offering a set of “standards, technology, and services” to countries and developers to plug into to get a standardized COVID-19 contacts-tracing approach up and running across the bloc.
The other very European flavored piece here is privacy — and privacy law. “Enforcement of data protection, anonymization, GDPR [the EU’s General Data Protection Regulation] compliance, and security” are baked in, is the top-line claim.
“PEPP-PR was explicitly created to adhere to strong European privacy and data protection laws and principles,” the group writes in an online manifesto. “The idea is to make the technology available to as many countries, managers of infectious disease responses, and developers as quickly and as easily as possible.
“The technical mechanisms and standards provided by PEPP-PT fully protect privacy and leverage the possibilities and features of digital technology to maximize speed and real-time capability of any national pandemic response.”
Hans-Christian Boos, one of the project’s co-initiators — and the founder of an AI company called Arago –discussed the initiative with German newspaper Der Spiegel, telling it: “We collect no location data, no movement profiles, no contact information and no identifiable features of the end devices.”
The newspaper reports PEPP-PT’s approach means apps aligning to this standard would generate only temporary IDs — to avoid individuals being identified. Two or more smartphones running an app that uses the tech and has Bluetooth enabled when they come into proximity would exchange their respective IDs — saving them locally on the device in an encrypted form, according to the report.
Der Spiegel writes that should a user of the app subsequently be diagnosed with coronavirus their doctor would be able to ask them to transfer the contact list to a central server. The doctor would then be able to use the system to warn affected IDs they have had contact with a person who has since been diagnosed with the virus — meaning those at risk individuals could be proactively tested and/or self-isolate.
On its website PEPP-PT explains the approach thus:
Mode 1
If a user is not tested or has tested negative, the anonymous proximity history remains encrypted on the user’s phone and cannot be viewed or transmitted by anybody. At any point in time, only the proximity history that could be relevant for virus transmission is saved, and earlier history is continuously deleted.Mode 2
If the user of phone A has been confirmed to be SARS-CoV-2 positive, the health authorities will contact user A and provide a TAN code to the user that ensures potential malware cannot inject incorrect infection information into the PEPP-PT system. The user uses this TAN code to voluntarily provide information to the national trust service that permits the notification of PEPP-PT apps recorded in the proximity history and hence potentially infected. Since this history contains anonymous identifiers, neither person can be aware of the other’s identity.
Providing further detail of what it envisages as “Country-dependent trust service operation”, it writes: “The anonymous IDs contain encrypted mechanisms to identify the country of each app that uses PEPP-PT. Using that information, anonymous IDs are handled in a country-specific manner.”
While on healthcare processing is suggests: “A process for how to inform and manage exposed contacts can be defined on a country by country basis.”
Among the other features of PEPP-PT’s mechanisms the group lists in its manifesto are:
- Backend architecture and technology that can be deployed into local IT infrastructure and can handle hundreds of millions of devices and users per country instantly.
- Managing the partner network of national initiatives and providing APIs for integration of PEPP-PT features and functionalities into national health processes (test, communication, …) and national system processes (health logistics, economy logistics, …) giving many local initiatives a local backbone architecture that enforces GDPR and ensures scalability.
- Certification Service to test and approve local implementations to be using the PEPP-PT mechanisms as advertised and thus inheriting the privacy and security testing and approval PEPP-PT mechanisms offer.
Having a standardized approach that could be plugged into a variety of apps would allow for contacts tracing to work across borders — i.e. even if different apps are popular in different EU countries — an important consideration for the bloc, which has 27 Member States.
However there may be questions about the robustness of the privacy protection designed into the approach — if, for example, pseudonymized data is centralized on a server that doctors can access there could be a risk of it leaking and being re-identified. And identification of individual device holders would be legally risky.
Europe’s lead data regulator, the EDPS, recently made a point of tweeting to warn an MEP (and former EC digital commissioner) against the legality of applying Singapore-style Bluetooth-powered contacts tracing in the EU — writing: “Please be cautious comparing Singapore examples with European situation. Remember Singapore has a very specific legal regime on identification of device holder.”
Dear Mr. Commissioner, please be cautious comparing Singapoore examples with European situation. Remember Singapore has a very specific legal regime on identification of device holder.
— Wojtek Wiewiorowski (@W_Wiewiorowski) March 27, 2020
A spokesman for the EDPS told us it’s in contact with data protection agencies of the Member States involved in the PEPP-PT project to collect “relevant information”.
“The general principles presented by EDPB on 20 March, and by EDPS on 24 March are still relevant in that context,” the spokesman added — referring to guidance issued by the privacy regulators last month in which they encouraged anonymization and aggregation should Member States want to use mobile location data for monitoring, containing or mitigating the spread of COVID-19. At least in the first instance.
“When it is not possible to only process anonymous data, the ePrivacy Directive enables Member States to introduce legislative measures to safeguard public security (Art. 15),” the EDPB further noted.
“If measures allowing for the processing of non-anonymised location data are introduced, a Member State is obliged to put in place adequate safeguards, such as providing individuals of electronic communication services the right to a judicial remedy.”
We reached out to the HHI with questions about the PEPP-PT project and were referred to Boos — but at the time of writing had been unable to speak to him.
“The PEPP-PT system is being created by a multi-national European team,” the HHI writes in a press release about the effort. “It is an anonymous and privacy-preserving digital contact tracing approach, which is in full compliance with GDPR and can also be used when traveling between countries through an anonymous multi-country exchange mechanism. No personal data, no location, no Mac-Id of any user is stored or transmitted. PEPP-PT is designed to be incorporated in national corona mobile phone apps as a contact tracing functionality and allows for the integration into the processes of national health services. The solution is offered to be shared openly with any country, given the commitment to achieve interoperability so that the anonymous multi-country exchange mechanism remains functional.”
“PEPP-PT’s international team consists of more than 130 members working across more than seven European countries and includes scientists, technologists, and experts from well-known research institutions and companies,” it adds.
“The result of the team’s work will be owned by a non-profit organization so that the technology and standards are available to all. Our priorities are the well being of world citizens today and the development of tools to limit the impact of future pandemics — all while conforming to European norms and standards.”
The PEPP-PT says its technology-focused efforts are being financed through donations. Per its website, it says it’s adopted the WHO standards for such financing — to “avoid any external influence”.
Of course for the effort to be useful it relies on EU citizens voluntarily downloading one of the aligned contacts tracing apps — and carrying their smartphone everywhere they go, with Bluetooth enabled.
Without substantial penetration of regional smartphones it’s questionable how much of an impact this initiative, or any contacts tracing technology, could have. Although if such tech were able to break even some infection chains people might argue it’s not wasted effort.
Notably, there are signs Europeans are willing to contribute to a public healthcare cause by doing their bit digitally — such as a self-reporting COVID-19 tracking app which last week racked up 750,000 downloads in the UK in 24 hours.
But, at the same time, contacts tracing apps are facing scepticism over their ability to contribute to the fight against COVID-19. Not everyone carries a smartphone, nor knows how to download an app, for instance. There’s plenty of people who would fall outside such a digital net.
Meanwhile, while there’s clearly been a big scramble across the region, at both government and grassroots level, to mobilize digital technology for a public health emergency cause there’s arguably greater imperative to direct effort and resources at scaling up coronavirus testing programs — an area where most European countries continue to lag.
Germany — where some of the key backers of the PEPP-PT are from — being the most notable exception.
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Rocket startup Skyrora shifts production to hand sanitizer and face masks for coronavirus response
One of the newer companies attempting to join the rarified group of private space launch startups actually flying payloads to orbit has redirected its entire UK-based manufacturing capacity towards COVID-19 response. Skyrora, which is based in Edinburgh, Scotland, is answering the call of the UK government and the NHS to manufacturers to do what they can to provide much-needed healthcare equipment for frontline responders amid the coronavirus crisis.
Skyrorary says that the entirety of its UK operations, including all human resources and its working capital are now dedicated to COVID-19 response. The startup, which was founded in 2017, had been working towards test flights of its first spacecraft, making progress including an early successful engine test using its experimental, more eco-friendly rocket fuel that was completed in February.
For now, though, Skyrora will be focusing full on building hand sanitizer, its first effort to support the COVID-19 response. The company has already produce their initial batch using WHO guidelines and requirements, and now aims to scale up its production efforts to the point where it can manufacture the sanitizer at a rate of over 10,000 250 ml bottles per week.
There’s actually a pretty close link between rocketry and hand sanitizer: Ethanol, the form of alcohol that provides the fundamental disinfecting ingredient for hand sanitizer, has been used in early rocket fuel. Skyrora’s ‘Ecosene’ fuel is a type of kerosene, however, which is a much more common modern aviation and rocket fuel.
In addition to sanitizer, Skyrora is now in talks with the Scottish Government to see where 3D-printed protective face masks might have a beneficial impact on ensuring health worker safety. It’s testing initial prototypes now, and will look to mass produce the protective equipment after those tests verify its output.
Plenty of companies are pitching in where they can, including by shifting their production lines and manufacturing capacity towards areas of greatest need. It’s definitely an ‘all-hands-on-deck’ moment, but there’s definitely a question of what happens to businesses that shift their focus this dramatically once the emergency passes, especially for young startups in emerging industries.
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Private tech companies mobilize to address shortages for medical supplies, masks and sanitizer
Startups across the nation and around the world are looking for ways to relieve shortages of much-needed personal protective equipment and sanitizers used to halt the spread of COVID-19.
While some of the largest privately held technology companies, like SpaceX and Tesla, have shifted to manufacturing ventilators, smaller companies are also trying to pitch in and relieve scarcity locally.
Supplies have been difficult to come by in some of the areas hardest hit by the outbreak of the novel coronavirus, and the shortfalls have been made worse by a lack of coordination from the federal government. In some instances local governments have been bidding for supplies against each other and the federal government to acquire needed personal protective equipment.
On Sunday, New York’s Governor Mario Cuomo pleaded with local governments to not engage in a bidding war. In fact, Kentucky was outbid by the federal government for personal protective equipment.
“FEMA came out and bought it all out from under us,” Kentucky Governor Andy Beshear told a local newspaper. “It is a challenge that the federal government says, ‘States, you need to go and find your supply chain,’ and then the federal government ends up buying from that supply chain.”
Against this backdrop local startups and maker spaces are stepping up to do what they can to fill the gap.
Alcohol brands are turning their attention to making hand sanitizer to distribute in communities experiencing shortages. 3D-printing companies are working on new ways to manufacture personal protective equipment and swabs for COVID-19 testing. And one fast fashion retail startup is teaching its tailors and seamstresses how to make cloth masks for consumer protection.
AirCo, a New York-based startup that developed a process to use captured carbon dioxide to make liquor, shifted its efforts to making hand sanitizer for donations in communities in New York City.
Now, new alcohol brands Bev and Endless West are joining the manufacturing push.
Endless West announced this morning that it would shift production away from its distillery to begin making hand sanitizers. The World Health Organization approved their sanitizers, which the company will produce in its warehouse in San Francisco.
The two-ounce bottles will be donated to local restaurants and bars that remain open for delivery, so that employees can use them and distribute them to customers. Bulk quantities will be distributed to healthcare organizations and facilities that need them.
Endless West also put out a call for other companies to provide supplies to hospitals and health organizations in the San Francisco Bay Area.
“We felt it was imperative to do our part and dedicate what resources we have to assist with shortages in the healthcare and food & beverage industries who keep the engine running and provide such important functions in this time of immense need throughout the community,” said Alec Lee, CEO of Endless West, in a statement.
Los Angeles-based Bev is no different.
“As an alcoholic beverage company, Bev is very lucky in that we are licensed to purchase ethanol directly from our suppliers, who are doing their part by discounting the product to anyone licensed to purchase it,” said Bev chief executive, Alix Peabody. “Community underscores everything we do here at Bev, and as such, we will be producing hand sanitizer and distributing it free of charge to the homeless and elderly communities here in Venice, populations who largely have insufficient access to healthcare and essential goods like sanitizer.”
Hand sanitizer is one sorely needed item in short supply, but there are others — including face masks, surgical masks, face shields, swabs and ventilator equipment that other startups are now switching gears to produce.
(Photo by PAU BARRENA/AFP via Getty Images)
In Canada, INKSmith, a startup that was making design and tech tools accessible for kids, has now moved to making face shields and is hiring up to 100 new employees to meet demand.
“I think in the short term, we’re going to scale up to meet the needs of the province soon. After that, we’re going to meet the demands of Canada,” INKSmith CEO Jeremy Hedges told the Canadian news outlet Global News.
3D-printing companies like Massachusetts-based Markforged and Formlabs are both making personal protective equipment like face shields, as well as nasal swabs to use for COVID-19 testing.
Markforged is pushing ahead with a number of efforts to focus some of the benefits of 3D printing on the immediate problem of personal protective equipment for healthcare workers most exposed to COVID-19.
“We have about 20 people working on this pretty much as much as they can,” said Markforged chief executive, Gregory Mark. “We break it up into three different programs. The first stage is prototyping validation and getting first pass to doctors. The second is clinical trials and the third is production. We are in clinical trials with two. One is the nasal swab and two is the face shield.”
The ability to spin up manufacturing more quickly than traditional production lines using 3D printing means that both companies are in some ways better positioned to address a thousandfold increase in demand for supplies that no one anticipated.
“3D printing is the fastest way to make anything in the world up to a certain number of days, weeks, months or years,” says Mark. “As soon as we get the green light from hospitals, 10,000 printers around the world can be printing face shields and nose swabs.”
Formlabs, which already has a robust business supplying custom-printed surgical-grade healthcare products, is pushing to bring its swabs to market quickly.
“Not only can we help in the development of the swabs, but we can manufacture them ourselves,” says Formlabs chief product officer, David Lakatos.
Swabs for testing are in short supply in part because there are only a few manufacturers in the world who made them — and one of those primary manufacturers is in Italy, which means supplies and staff are in short supply. “There’s a shortage of them and nobody was expecting that we would need to test millions of people in short order,” says Lakatos.
Formlabs is also working on another piece of personal protective equipment — looking at converting snorkeling masks into respirators and face masks. “Our goal is to make one that is reusable,” says Lakatos. “A patient can use it as a respirator and you can put it in an autoclave and reuse it.”
In Brooklyn, Voodoo Manufacturing has repurposed its 5,000-square-foot facility to mass-produce personal protective equipment. The company has set up a website, CombatingCovid.com, where organizations in need of supplies can place orders. Voodoo aims to print at least 2,500 protective face shields weekly and can scale to larger production volumes based on demand, the company said.
STAMFORD, CT – MARCH 23: Nurse Hannah Sutherland, dressed in personal protective equipment (PPE) awaits new patients at a drive-thru coronavirus testing station at Cummings Park on March 23, 2020 in Stamford, Connecticut. Availability of protective clothing for medical workers has become a major issue as COVID-19 cases surge throughout the United States. The Stamford site is run by Murphy Medical Associates. (Photo by John Moore/Getty Images)
Finally, Resonance, the fast fashion startup launched by the founder of FirstMark Capital, Lawrence Lenihan, is using its factory in the Dominican Republic to make face masks for consumers on the island and beyond.
“To contribute to the Dominican health efforts, Resonance is acting to utilize their resources to manufacture safety masks for distribution to local hospitals, nursing homes, and other high-risk facilities as quickly as possible. They have provided user-friendly instructions and material and will pay their sewers who can to make these masks from the security of their homes,” a spokesperson for the company wrote in an email. “Resonance is currently working to share this downloadable platform and simple instructions to their website, so anyone in the world can contribute to their own local communities.”
All of these efforts — and countless others too numerous to mention — point to the ways small companies are hoping to do something to help their communities stay safe and healthy in the midst of this global outbreak.
But many of these extreme measures may not have been necessary had governments around the world actively coordinated their response and engaged in better preparation before the situation became so dire.
There are a litany of errors that governments made — and are still making — in their efforts to respond to the pandemic, even as the private sector steps in and steps up to address them.
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Israel passes emergency law to use mobile data for COVID-19 contact tracing
Israel has passed an emergency law to use mobile phone data for tracking people infected with COVID-19 including to identify and quarantine others they have come into contact with and may have infected.
The BBC reports that the emergency law was passed during an overnight sitting of the cabinet, bypassing parliamentary approval.
Israel also said it will step up testing substantially as part of its respond to the pandemic crisis.
In a statement posted to Facebook, prime minister Benjamin Netanyahu wrote: “We will dramatically increase the ability to locate and quarantine those who have been infected. Today, we started using digital technology to locate people who have been in contact with those stricken by the Corona. We will inform these people that they must go into quarantine for 14 days. These are expected to be large – even very large – numbers and we will announce this in the coming days. Going into quarantine will not be a recommendation but a requirement and we will enforce it without compromise. This is a critical step in slowing the spread of the epidemic.”
“I have instructed the Health Ministry to significantly increase the number of tests to 3,000 a day at least,” he added. “It is very likely that we will reach a higher figure, even up to 5,000 a day. To the best of my knowledge, relative to population, this is the highest number of tests in the world, even higher than South Korea. In South Korea, there are around 15,000 tests a day for a population five or six times larger than ours.”
On Monday an Israeli parliamentary subcommittee on intelligence and secret services discussed a government request to authorize Israel’s Shin Bet security service to assist in a national campaign to stop the spread of the novel coronavirus — but declined to vote on the request, arguing more time is needed to assess it.
Civil liberties campaigners have warned the move to monitor citizens’ movements sets a dangerous precedent.
Netanyahu’s announcement that he intends to bypass parliamentary oversight and implement emergency regulations that authorize the Shin Bet to locate Corona patients actualizes this danger.
— ACRI (@acri_online) March 16, 2020
According to WHO data, Israel had 200 confirmed cases of the coronavirus as of yesterday morning. Today the country’s health ministry reported cases had risen to 427.
Details of exactly how the tracking will work have not been released — but, per the BBC, the location data of people’s mobile devices will be collected from telcos by Israel’s domestic security agency and shared with health officials.
It also reports the health ministry will be involved in monitoring the location of infected people to ensure they are complying with quarantine rules — saying it can also send text messages to people who have come into contact with someone with COVID-19 to instruct them to self isolate.
In recent days Netanyahu has expressed frustration that Israel citizens have not been paying enough mind to calls to combat the spread of the virus via voluntary social distancing.
“This is not child’s play. This is not a vacation. This is a matter of life and death,” he wrote on Facebook. “There are many among you who still do not understand the magnitude of the danger. I see the crowds on the beaches, people having fun. They think this is a vacation.”
“According to the instructions that we issued yesterday, I ask you not leave your homes and stay inside as much as possible. At the moment, I say this as a recommendation. It is still not a directive but that can change,” he added.
Since the Israeli government’s intent behind the emergency mobile tracking powers is to combat the spread of COVID-19 by enabling state agencies to identify people whose movements need to be restricted to avoid them passing the virus to others, it seems likely law enforcement agencies will also be involved in enacting the measures.
That will mean citizens’ smartphones being not just a tool of mass surveillance but also a conduit for targeted containment — raising questions about the impact such intrusive measures might have on people’s willingness to carry mobile devices everywhere they go, even during a pandemic.
Yesterday the Wall Street Journal reported that the US government is considering similar location-tracking technology measures in a bid to check the spread of COVID-19 — with discussions ongoing between tech giants, startups and White House officials on measures that could be taken to monitor the disease.
Last week the UK government also held a meeting with tech companies to ask for their help in combating the coronavirus. Per Wired some tech firms offered to share data with the state to help with contact tracing — although, at the time, the government was not pursuing a strategy of mass restrictions on public movement. It has since shifted position.
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Verizon increases network infrastructure investment by $500M
Verizon said Thursday it will boost investment in network infrastructure, increasing its capital guidance by $500 million, to prepare for the rise in telecommuting and online learning amid the coronavirus outbreak.
Verizon has not seen any measurable increases in data usage, even as some business, schools and other organizations are asking its employees to work remotely, Chairman and CEO Hans Vestberg told CNBC in an interview. He added that the company is monitoring it 24/7 because “patterns can change.” (TechCrunch is owned by Verizon.)
Still, the company is increasing its capital guidance from $17 billion-$18 billion to $17.5 billion-$18.5 billion in 2020. Vestberg said the company would continue to add to its network infrastructure. Verizon said in a statement that the effort aims to accelerate the company’s transition to 5G and help support the economy during this period of disruption.
“In these times, it’s important to show the market and the country that there are people investing as well,” he added in the CNBC interview.
Verizon said in a statement that it has been closely monitoring network usage in the most impacted areas and will work with and prioritize network demand to assist needs of U.S. hospitals, first responders and government agencies.
The decision follows an escalating global crisis caused by COVID-19, the coronavirus strain that was declared a pandemic by the World Health Organization earlier this week. COVID-19 has wreaked havoc on the stock market, pushing shares lower in every industry, and caused numerous closures, including professional sports games, the cancellation of the NCAA March Madness basketball tournament and Disneyland. Shares of Verizon closed down 3.65%, at $51.20.
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A list of MWC coronavirus cancellations so far: Facebook, AT&T, Sprint, Intel now also staying away
Yet more big names are being added to the list of companies that are staying away from the world’s biggest mobile tradeshow, Mobile World Congress (MWC), with Facebook and Intel among the latest to cancel their attendance. Due to take place in Barcelona just under two weeks’ time, on February 24-27, the event has been hampered by the ongoing situation with the novel coronavirus outbreak.
“Out of an abundance of caution, Facebook employees won’t be attending this year’s Mobile World Congress due to the evolving public health risks related to coronavirus,” said a spokesperson for Facebook, in a message worded not unlike a number of others that have been put out by others choosing not to attend. “We will continue to collaborate with the GSMA and our partners and thank them for their efforts.”
Spanish publication El Pais is also reporting that the GSMA, the body that organizes the event, is due to meet on Friday and consider its next steps, which could include suspending the event. It also notes that major carriers Vodafone and Deutsche Telekom are also considering options, although nothing has been confirmed yet. Orange has told us it still intends to participate.
We have reached out to the GSMA and it has declined to comment on the El Pais report. “We don’t comment on internal meetings,” the spokesperson said. (The GSMA would be meeting regularly regardless in the lead-up to the event.)
The annual international telco industry event typically attracts more than 100,000 delegates from around 200 countries across the conference’s four days — with every major telco and tech giant exhibiting (with the exception of Apple which prefers its own events).
But with international concern now focused on the novel coronavirus outbreak — which was declared a global emergency by the World Health Organization late last month and as of today has infected over 40,000 people with more than 1,000 deaths — a growing number of companies have announced they are pulling out of attending.
Others, such as Telenor, TCL and ZTE, have cancelled press events or said they will scale back their presence though are still planning to attend. Today Chinese phone maker Xiaomi also confirmed it will attend — tweeting a statement detailing the precautions it’s taking.
Having carriers pulling out of the event is a huge deal, since they are the key “buyers” at the trade show and at the heart of the organization, the GSMA, that is behind it. And while big tech companies like Facebook are a newer, but now very regular, presence the event — which underscores how MWC has changed over the years, and how the mobile industry is trying to evolve with the times, where “tech” and “telco” are no longer distinct entities — they are nonetheless leaving a large hole in the makeup of the show by not being there.
The GSMA has announced a series of restrictions intended to reduce the risk of the coronavirus infections at the conference, including a ban on travellers coming from the province in China where the virus was first identified. It has also said it will implement temperature screening of attendees; require conference-goers self-certify they have not come into contact with an infected person; and is suggesting delegates adopt a ‘no hand shake’ policy in a bid to limit contact.
There is a lot riding on MWC going ahead. The El Pais report notes that MWC generates some 14,000 temporary jobs and generates €492 million (nearly $540 million) for the city. Per the GSMA site, more than 2,400 companies are exhibiting at MWC this year. Yesterday, a spokesperson told TechCrunch that MWC had 2,800 companies signed up to exhibit, but it’s not sharing how many are still going to be there.
See below for a list of companies that have cancelled their attendance at the conference — we’ll update with any additions as we get them.
Organizations that have cancelled their attendance at MWC 2020
ARCEP, France’s FCC (confirmed via email)
AT&T (confirmed via email)
F5 Networks (confirmed via email)
Facebook (confirmed via email)
Gigaset (confirmed via email)
KMW Communications (confirmed via email)
Radwin (confirmed via email)
Rakuten (confirmed via email)
Sprint (confirmed via email)
Viber (confirmed via email)
This article was updated with a correction to remove ‘Rakuten’ from the list of cancellations after an earlier spokesperson provided us with incorrect information. And in a further update, the CEO of Viber, owned by Rakuten, also said the messaging app would be attending after all:
“As of today Viber will have a presence at MWC, including me,” said Djamel Agaoua. “Like all companies, we are evaluating the risk to our employees and if our position changes we will keep you updated. Sorry about the confusion.”
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