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AI services startup Hypergiant brings on Bill Nye as an advisor

Hypergiant, a startup launched last year to address the execution gap in bringing applied AI and machine learning technologies to bear for large companies, has signed on a high-profile new advisor to help out with the new ‘Galactic Systems’ division of its services lineup.

Hypergiant founder CEO Ben Lamm also serves as an Advisory Council Member for The Planetary Society, the nonprofit dedicated to space science and exploration advocacy that’s led by Nye who acts as the Society’s CEO. Nye did some voiceover work for the video at the bottom of this post for Hypergiant through the connection, and then decided to come on in a more formal capacity as an official advisor working with the company. He’ll act as a member of Hypergiant’s Advisory Board.

Nye was specifically interested in helping Hypergiant to work on AI tech that touch on a couple of areas he’s most passionate about.

“Hypergiant has an ambitious mission to address some big problems using artificial intelligence systems,” Nye explained via email. “I’m looking forward to working with Hypergiant to develop artificially intelligent systems in two areas I care about a great deal: climate change and space exploration. We need to think big, and I’m very optimistic about what AI can do to make the world quite a bit better.”

Through its work, Hypergiant has an impact on projects in flight from high-profile customers including Apple, GE, Starbucks and the Department of Homeland Security to name just a few. Earlier this year, Austin-based Hypergiant announced it was launching a dedicated space division through the acquisition of Satellite & Extraterrestrial Operations & Procedures (SEOPS), a Texas company that offered deployment services for small satellites.

Ben Lamm NASA 2

Hypergiant founder and CEO Ben Lamm along with members of the Hypergiant team at NASA. Credit: Hypergiant.

Nye’s role will focus on this division, advising on space, but also equally on advising clients as to climate change in order to ensure that Hypergiant can “make the most of AI systems to hep provide a high quality of life for people everywhere,” Nye wrote.

“Climate change is the biggest issue we face, and we need to get serious about new ways to fight it,” he explained in an email, noting that the potential impact his work with Hypergiant will have in this area specifically is a key reason he’s excited to undertake the new role.

A Better World from HYPERGIANT on Vimeo.

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This robot crawls along wind turbine blades looking for invisible flaws

Wind turbines are a great source of clean power, but their apparent simplicity — just a big thing that spins — belie complex systems that wear down like any other, and can fail with disastrous consequences. Sandia National Labs researchers have created a robot that can inspect the enormous blades of turbines autonomously, helping keep our green power infrastructure in good kit.

The enormous towers that collect energy from wind currents are often only in our view for a few minutes as we drive past. But they must stand for years through inclement weather, temperature extremes, and naturally — being the tallest things around — lightning strikes. Combine that with normal wear and tear and it’s clear these things need to be inspected regularly.

But such inspections can be both difficult and superficial. The blades themselves are among the largest single objects manufactured on the planet, and they’re often installed in distant or inaccessible areas, like the many you see offshore.

“A blade is subject to lightning, hail, rain, humidity and other forces while running through a billion load cycles during its lifetime, but you can’t just land it in a hanger for maintenance,” explained Sandia’s Joshua Paquette in a news release. In other words, not only do crews have to go to the turbines to inspect them, but they often have to do those inspections in place — on structures hundreds of feet tall and potentially in dangerous locations.

Using a crane is one option, but the blade can also be orientated downwards so an inspector can rappel along its length. Even then the inspection may be no more than eyeballing the surface.

“In these visual inspections, you only see surface damage. Often though, by the time you can see a crack on the outside of a blade, the damage is already quite severe,” said Paquette.

Obviously better and deeper inspections are needed, and that’s what the team decided to work on, with partners International Climbing Machines and Dophitech. The result is this crawling robot, which can move along a blade slowly but surely, documenting it both visually and using ultrasonic imaging.

A visual inspection will see cracks or scuffs on the surface, but the ultrasonics penetrate deep into the blades, making them capable of detecting damage to interior layers well before it’s visible outside. And it can do it largely autonomously, moving a bit like a lawnmower: side to side, bottom to top.

Of course at this point it does it quite slowly and requires human oversight, but that’s because it’s fresh out of the lab. In the near future teams could carry around a few of these things, attach one to each blade, and come back a few hours or days later to find problem areas marked for closer inspection or scanning. Perhaps a crawler robot could even live onboard the turbine and scurry out to check each blade on a regular basis.

Another approach the researchers took was drones — a natural enough solution, since the versatile fliers have been pressed into service for inspection of many other structures that are dangerous for humans to get around: bridges, monuments, and so on.

These drones would be equipped with high-resolution cameras and infrared sensors that detect the heat signatures in the blade. The idea is that as warmth from sunlight diffuses through the material of the blade, it will do so irregularly in spots where damage below the surface has changed its thermal properties.

As automation of these systems improves, the opportunities open up: A quick pass by a drone could let crews know whether any particular tower needs closer inspection, then trigger the live-aboard crawler to take a closer look. Meanwhile the humans are on their way, arriving to a better picture of what needs to be done, and no need to risk life and limb just to take a look.

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Scientists discover a new way to provide plants the nutrients they need to thrive

Researchers at Carnegie Mellon University have discovered a new method for delivering key nutrients to plant roots – without having to ensure they’re present in the soil where the plants are growing.

The landmark study greatly increases the efficiency of surface delivery of nutrients and pesticides to plants. Currently, when crops are sprayed with stuff that’s supposed to help them grow faster or better, the vast majority of that (up to 95 percent, according to CMU’s engineering blog) will just end up either as concentrated deposits in the surrounding soil, or dissolving into ground water. In both cases, accumulation over time can have negative knock-on effects, in addition to being terribly inefficient at their primary task.

This method, described by researchers in detail in a new academic paper, would manage to improve efficiency to nearly 100% absorption of nutrients and pesticides delivered as nanoparticles (particles smaller than 50 nanometers across – a human hair is about 75,000 nanometers wide, for context) sprayed onto the leaves of plants, which then make their way through the plant’s internal vascular system all the way down into the root system.

Using this method, agricultural professionals could also greatly improve delivery of plant antibiotics, making it easier and more cost-effective to treat plant diseases affecting crop yields. It would be cheaper to delivery all nutrients and pesticides, too, because the big bump in efficiency of uptake by the plants means you can use much less of anything you want to deliver to achieve your desired effect.

This research could have huge impact in terms of addressing growing global food supply needs while making the most existing agricultural land footprint and decreasing the need for potentially damaging expansion of the same.

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Space startup Wyvern wants to make data about Earth’s health much more accessible

The private space industry is seeing a revolution driven by cube satellites, which are affordable, lightweight satellites that are much easier than traditional satellites to design, build and launch. It’s paving the way for new businesses like Wyvern, an Alberta-based startup that provides a very specific service that wouldn’t even have been possible to offer a decade ago: Relatively low-cost access to hyperspectral imaging taken from low-Earth orbit, which is a method for capturing image data of Earth across many more bands than we’re able to see with our eyes or traditional optics.

Wyvern’s founding team, including CEO Chris Robson, CTO Kristen Cote, CSO Callie Lissinna and VP of Engineering/COO Kurtis Broda, had experience building satellites through their schooling, including working on building the first-ever satellite in space designed and built in Alberta, Ex-Alta 1. They’ve also developed their own proprietary optical technology to develop the kind of imagery that will best serve the needs of the clients they’re pursuing. Their first target market, for instance, are farmers, who will be able to log into the commercial version of their product and get up-to-date hyperspectral imaging data of their fields, which can help them optimize yield, detect changes in soil makeup (which will tell them if they have too little nitrogen) or even help them spot invasive plants and insects.

“We’re doing all sorts of things that directly affect the bottom line of farmers,” explained Robson in an interview. “If you can detect them, and you can quantify them, and the farmers can make decisions on how to act and ultimately how to increase the bottom line. A lot of those things you can’t do with multi-spectral [imaging] right now, for example, you can’t speciate with multi-spectral, so you can’t detect invasive species.”

Multi-spectral imaging, in contrast to hyperspectral imaging, measures light on average in between three to 15 bands, while hyperspectral can manage as many as hundreds of adjoining or neighboring bands, which is why it can do more specialist things like identifying the species of animals on the ground in an observed area from a satellite’s perspective.

Hyperspectral imaging is already a proven technology in use around the world for exactly these purposes, but the main way it’s captured is via drone airplanes, which Robson says is much more costly and less efficient than using CubeSats in orbit.

“Drone airplanes are really expensive, and with us, we’re able to provide it for 10 times less than a lot of these drones currently in use,” he said.

Wyvern’s business model will focus on owning and operating the satellites; providing access to the data, it caters to customers in a way that’s easy for anyone to access and use.

“Our key differentiator is the fact that we allow access to actual actionable information,” Robson said. “Which means that if you want to order imagery, you do it through a web browser, instead of calling somebody up and waiting one to three days to get a price on it, and to find out whether they could even do what you’re asking.”

Robson says that it’s only even become possible and affordable to do this because of advances in optics (“Our optical system allows us to basically put what should be a big satellite into the form factor of a small one without breaking the laws of physics,” Robson told me), small satellites, data storage and monitoring stations, and privatized launches making space accessible through hitching a ride on a launch alongside other clients.

Wyvern will also occupy its own, underserved niche providing this highly specialized info, first to agricultural clients, and then expanding to five other verticals, including forestry, water quality monitoring, environmental monitoring and defense. This isn’t something other more generalist satellite imaging providers like Planet Labs will likely be interested in pursuing, Robson said, because it’s an entirely different kind of business with entirely different equipment, clientele and needs. Eventually, Wyvern hopes to be able to open more broadly access to the data it’s gathering.

“You have the right to access [information regarding] the health of the Earth regardless of who you are, what government you’re under, what country you’re a part of or where you are in the world,” he said. “You have the right to see how other humans are treating the Earth, and to see how you’re treating the Earth and how your country is behaving. But you also have the right to take care of the Earth, because we’re super predators. We’re the most intelligent species. We are; we have the responsibility of being stewards of the Earth. And part of that, though, is being able to add almost omniscience of what’s going on in the Earth in the same way that we understand what’s going on in our bodies. That’s what we want for people.”

Right now, Wyvern is very early on the trajectory of making this happen — they’re working on their first round of funding, and have been speaking to potential customers and getting their initial product validation work finalized. But with actual experience building and launching satellites, and a demonstrated appetite for what they want to build, it seems like they’re off to a promising start.

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Orbit Fab becomes first startup to supply water to ISS, paving the way for satellite refueling

Not even two years into its existence, orbital fuel supply startup Orbit Fab has chalked up a big win — successfully supplying the International Space Station with water, a first for any private company. It’s a big deal, because providing water to the ISS involved a multi-day refueling process, done in microgravity, using processes and equipment Orbit Fab developed itself.

The key ingredient here, per ISS U.S. National Laboratory COO Kenneth Shields, which was the contracting agency for Orbit Fab’s refueling test, is that this method of resupply is totally out of spec in terms of how this process was designed to work on the ISS. By creating and successfully demonstrating a system that the ISS designers never conceived, Orbit Fab has shown that both private companies and NASA have the flexibility needed to build business models on existing space infrastructure.

The technology Orbit Fab developed and demonstrated has broader applications than just moving water around in space. Water was used in this example specifically because it’s one of the most inert propellants used in spaceflight thrusters, but the methods could extend to other common propellants, and make it possible to refuel satellites in orbit. Orbit Fab is working toward establishing standards for satellite refueling interfaces to be used in orbital hardware, which could go a long way toward making it common practice to develop reusable satellites, instead of sticking with the more or less disposable hardware model used today.

Startups like Orbit Fab are the key to unlocking true commercialization of space, by identifying points in the value chain where innovation or improvement can lead to cost or resource efficiencies and ensure that space business is actually also viable business, in terms of profit potential.

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What top VCs look for in women’s fertility startups

A number of promising women’s health tech companies have popped up in the last few years, from fertility apps to ovulation bracelets — even Apple has jumped into the subject with the addition of period tracking built into the latest edition of the watch. But there hasn’t been much in the way of innovation in women’s sexual health for decades.

In-vitro fertilization (IVF) is now a 40-year-old invention and even the top pharmaceutical companies have spent a pittance on research and development. Subjects like polycystic ovarian syndrome, endometriosis and menopause have taken a backseat to other, more fatal concerns. Fertility is itself oftentimes a mysterious black box as well, though a full 10% of the female population in the United States has difficulty getting or staying pregnant.

That’s all starting to change as startups are now bringing in millions in venture capital to gather and treat women’s health. While it’s early days (no unicorns just yet) interest in the subject has been jumping steadily higher each year.

To shine a better light on the importance of tech’s role in spurring more innovation for women’s fertility, we asked five VCs passionate about the space for their investment strategies, including Sarah Cone (Social Impact Capital), Vanessa Larco (NEA), Anu Duggal (Female Founders Fund), Jess Lee (Sequoia) and Nancy Brown (Oak HC/FT).

Sarah Cone, Social Impact Capital

Sarah Cone, Social Impact Capital

We’re interested in companies that create large data sets in women’s health and fertility, enabling personalized medicine, clinical trial virtualization, better patient outcomes, and the application of modern AI/ML techniques to generate hypotheses that discover new targets and molecules.

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KLM Airlines wants to help build a more efficient jet with in-wing seating

Air travel accounts for a significant chunk of greenhouse gas emissions and other pollutants, and the amount of air travel has risen steadily over the past few decades, with emissions from aviation predicted to grow significantly through 2020 and beyond. Electric passenger planes are in the works, but unlikely to replace our workhorse passenger jets any time soon — which is why efforts like a new type of conventional-fuel aircraft are being backed by KLM Airlines.

The new aircraft design was conceived by designer Justus Benad and is being further realized by a team of researchers at the Netherlands’ Delft University of Technology, per CNN. The look of the aircraft is clearly different from the start, ditching the typical cylindrical tube main fuselage for a “squat slice of pizza” look that extends the body through the wings of the plane.

This beefed-up core holds passengers, fuel and cargo, and through this distribution, which improves the aircraft’s overall aerodynamics, the plane will manage to be 20% more fuel-efficient versus the Airbus A350, which carries approximately the same amount of passengers depending on its configuration.

A savings of 20% in fuel consumption may not seem like much, but over time, and at scale, it could potentially make a huge difference — especially if the pace of electric aircraft development and other alternatives doesn’t pick up. That said, timelines for deployment aren’t super immediate: These could enter service sometime between 2040 and 2050 based on the current development schedule, which isn’t exactly tomorrow.

Testing an all-new design for passenger jets, which basically look like they did when they were first introduced, is obviously not something one undertakes lightly, however. The good news is that the team is hoping to put a scale model into real-world flight testing later this year.

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Where are all the biotech startups raising?

Jason Rowley
Contributor

Jason Rowley is a venture capital and technology reporter for Crunchbase News.

Where are all the biotechnology companies raising these days? We crunched some numbers to arrive at an answer.

Using funding rounds data from Crunchbase, we plotted the count of venture capital funding rounds raised by companies in the fairly expansive biotechnology category in Crunchbase. Click the chart below and you can hover over individual data points to see the number of venture rounds raised in a given metro area between the start of 2018 and late May 2019 (as of publication). Although there are biotechnology companies located throughout the world, we focused here on just the U.S.

USA_Biotech_2018-May2019

Unlike in the software-funding business, where New York City (and its surrounding area) ranks second in overall deal volume, the greater Boston metro area outranks the Big Apple in biotech venture deal volume. The SF Bay Area (which includes both San Francisco and the towns in Silicon Valley north and west of San Jose) outranks Boston in biotech deal volume, but, then again, it’s also a much larger geographic area with a higher density of startups overall.

The bio business model breeds big deals

Crunchbase News recently covered a $120 million round raised by immunotherapy upstart AlloVir. In the software business, a raise that large would be notable; however, in the business of biology, not so much.

Just for reference, the average Series B round raised by U.S. enterprise software startups between 2018 and May 2019 was about $22.7 million. The average Series B for biotech companies from that same time period: just about $40 million on the dot.

Spinning up a cluster of cells at a lab bench is costlier, harder to do and the outcomes of experiments are less certain than the results of implementing a new software framework. Add to that the tremendous cost of performing clinical trials and clearing regulatory hurdles — all before costly sales and marketing campaigns to get treatments in front of doctors and end users — and it’s easy to understand why many biotechnology companies need to raise so much money in the early stages of the startup cycle.

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Groupon co-founder Eric Lefkofsky just raised another $200 million for his newest company, Tempus

When serial entrepreneur Eric Lefkofsky grows a company, he puts the pedal to the metal. When in 2011 his last company, the Chicago-based coupons site Groupon, raised $950 million from investors, it was the largest amount raised by a startup, ever. It was just over three years old at the time, and it went public later that same year.

Lefkofsky seems to be stealing a page from the same playbook for his newest company, Tempus. The Chicago-based genomic testing and data analysis company was founded a little more than three years ago, yet it has already hired nearly 700 employees and raised more than $500 million — including through a new $200 million round that values the company at $3.1 billion.

According to the Chicago Tribune, that new valuation makes it — as Groupon once was — one of Chicago’s most highly valued privately held companies.

So why all the fuss? As the Tribune explains it, Tempus has built a platform to collect, structure and analyze the clinical data that’s often unorganized in electronic medical record systems. The company also generates genomic data by sequencing patient DNA and other information in its lab.

The goal is to help doctors create customized treatments for each individual patient, Lefkofsky tells the paper.

So far, it has partnered with numerous cancer treatment centers that are apparently giving Tempus human data from which to learn. Tempus is also generating data “in vitro,” as is another company we featured recently called Insitro, a drug development startup founded by famed AI researcher Daphne Koller. With Insitro, it is working on a liver disease treatment owing to a tie-up with Gilead, which has amassed related human data over the years from which Insitro can use to learn. As a complementary data source, Insitro, like Tempus, is trying to learn what the disease does in a “dish,” then determine if it can use what it observes using machine learning to predict what it sees in people.

Tempus hasn’t come up with any cancer-related cures yet, but Lefkofsky already says that Tempus wants to expand into diabetes and depression, too.

In the meantime, he tells Crain’s Chicago Business that Tempus is already generating “significant” revenue. “Our oldest partners, have, in most cases, now expanded to different subgroups (of cancer). What we’re doing is working.”

Investors in the latest round include Baillie Gifford; Revolution Growth; New Enterprise Associates; funds and accounts managed by T. Rowe Price; Novo Holdings; and the investment management company Franklin Templeton.

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Delane Parnell’s plan to conquer amateur esports

Most of the buzz about esports focuses on high-profile professional teams and audiences watching live streams of those professionals.

What gets ignored is the entire base of amateurs wanting to compete in esports below the professional tier. This is like talking about the NBA and the value of its sponsorships and broadcast rights as if that is the entirety of the basketball market in the US.

Los Angeles-based PlayVS (pronounced “play versus”) wants to become the dominant platform for amateur esports, starting at the high school level. The company raised $46 million last year—its first year operating—with the vision that owning the infrastructure for competitions and expanding it to encompass other social elements of gaming can make it the largest gaming company in the world.

I recently sat down with Founder & CEO Delane Parnell to talk about his company’s formation and growth strategy. Below is the transcript of our conversation (edited for length and clarity):

Founding PlayVS

Eric P: You have a fascinating background as a serial entrepreneur while you were a teenager.

Delane P.: I grew up on the west side of Detroit and started working at the cell phone store of a family friend when I was 13. When I turned 16 or so, I joined two guys in opening our own Metro PCS franchise. And then two additional franchises. And I was on the founding team of a car rental company called Executive Rental Car.

Eric P: And this segued into tech startups after meeting Jon Triest from Ludlow Ventures?

Delane P: He got me a ticket to the Launch conference in SF, and that experience inspired me to start a Fireside Chat series in Detroit that brought in people like Brian Wong from Kiip and Alexis Ohanian from Reddit to speak. Starting at 21, I worked at a venture capital firm called IncWell based in Birmingham, Michigan then joined a startup called Rocket Fiber.

We were focused on internet infrastructure – this is 2015-ish – and I was appointed to lead our strategy in esports. So I met with many of the publishers, ancillary startups, tournament organizers, and OG players and team owners. Through the process, I became passionate about esports and ended up leaving Rocket Fiber to start a Call of Duty team that I quickly sold to TSM.

Eric P: What then drove you to found PlayVS? Did it seem like an obvious opportunity or did it take you a while to figure it out?

Delane P.: What esports means is playing video games competitively bound to governance and a competitive ruleset. As a player, what that experience means is you play on a team, in a position, with a coach, in a season that culminates in some sort of championship.

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