obesity

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Ro makes the weight loss product Plenity commercially available to everyone in the US

In what could be the first step in the development of a significant new line of business for the telemedicine prescription provider Ro, the company is finally announcing the general commercial availability of weight loss product, Plenity.

Developed by Gelesis, a biotech company that makes treatments for gastro-intestinal disorders, Plenity is a weight loss treatment that uses citric acid and cellulose to create a non-toxic paste that makes people feel more full after they ingest it. Taken before meals, the pill becomes a substance that expands to take up about 25% of the stomach, so people eat less.

The product has been approved by the U.S. Food and Drug Administration and is available for a much broader segment of the population than other weight loss products. While most prescription medicines are intended for people who are obese, the Gelesis product is made for people who are overweight, too.

“That’s adults who have a BMI from 25 up to 40. That’s 150 million Americans,” according to Gelesis chief commercial and operating officer, David Pass.

Plenity received FDA approval last April, and Gelesis started working with Ro soon after, according to Pass. The idea was to craft a strategy that could get the treatment, which is classified as a medical device and not a drug, in the hands of as many patients as quickly as possible.

For Ro, the agreement with Gelesis is a sign of potential things to come. The company is the exclusive online provider of the Plenity treatment and Ro founder Zachariah Reitano said that there’s an incredible potential to engage in more of these types of deals.

“We would love to be able to partner with pharmaceutical companies to decrease the cost of distribution,” said Reitano. “We were excited to build an exciting treatment solution for weight management. Our high-level mission is to be the patient’s first call.”

With the Gelesis partnership Ro can add another highly desirable treatment to its roster of therapies — and one that can be a contributing factor to increasing the severity of other conditions that the company already provides treatment for, Reitano said. 

“There are a few conditions that we currently treat that are exacerbated by a patient being overweight or obese. People who struggle with weight management will also experience ED. Obesity can lead to heart failure, stroke, coronary heart disease, hypertension, depression,” Reitano said. “The breadth of the label is interesting. Only FDA approved with a BMI from 25 to 40. FDA approved treatment have been between 30 and 40. [It] makes the treatment more accessible to a wider variety of people.”

As the only online provider of the treatment, Ro has developed an onboarding process to ensure that the Plenity therapy isn’t abused by people who suffer from eating disorders.

“During our onboarding we not only ask questions to patients about their weight management. There’s a consecutive set of images that need to be uploaded and taken with the provider. That’s something we’ve taken a lot of time and energy to make sure about,” said Reitano. 

Like the other treatments Ro offers, Plenity is a cash-pay prescription, because the weight loss treatments aren’t typically covered by insurance, he said.

The benefit of working with an online pharmacy like Ro to provide distribution for a new therapy was obvious to both startups.

“We turned this market on its head by putting the consumer at the heart of everything we do,” said Pass. The treatment costs $98 per month, compared to other therapies or branded medications that could be as much $300 and $350 per month, according to Pass.

One reason that Gelesis is able to reduce the price of the drug is that it won’t have to hire a massive sales force to pitch it. The company has Ro for that.

“Normally you have a pharmaceutical company that would have to hire a sales force and go door to door and it increases the cost of a new drug. [Ro] can make a new, innovative treatment, like Plenity, available nationwide,” Reitano said. 

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WW launches Kurbo, a hotly debated ‘healthy eating’ app aimed at kids

Kurbo Health, a mobile weight loss solution designed to tackle childhood obesity which was acquired for $3 million by WW (the rebranded Weight Watchers), has now relaunched as Kurbo by WW — and not without some controversy. Pre-acquisition, the startup was focused on democratizing access to research, behavior modification techniques and other tools that were previously only available through expensive programs run by hospitals or other centers.

As a WW product, however, there are concerns that parents putting kids on “diets” will lead to increased anxiety, stress and disordered eating — in other words, Kurbo will make the problem worse, rather than solving it.

*If* you are worried about your child’s health/lifestyle, give them plenty of nutritious food and make sure they get plenty of fun exercise that helps their mental health. And don’t weigh them. Don’t burden them with numbers, charts or “success/failure.” It’s a slippery slope.

— Jameela Jamil 🌈 (@jameelajamil) August 14, 2019

The Kurbo app first launched at TechCrunch Disrupt NY 2014. Founder Joanna Strober, a venture investor and board member at BlueNile and eToys, explained she was driven to develop Kurbo after struggling to help her own child. Mainly, she came across programs that cost money, were held at inconvenient times for working parents or were dubbed “obesity centers” — with which no child wanted to be associated.

Her child found eventual success with the Stanford Pediatric Weight Loss Program, but this involved in-person visits and pen-and-paper documentation.

Together with Kurbo Health’s co-founder Thea Runyan, who has a Master’s in Public Health and had worked at the Stanford center for 12 years, the team realized the opportunity to bring the research to more people by creating a mobile, data-driven program for kids and families.

They licensed Stanford’s program, which then became Kurbo Health.

FoodSystem Phone

The company raised funds from investors, including Signia Ventures, Data Collective, Bessemer Venture Partners and Promus Ventures, as well as angels like Susan Wojcicki, CEO of YouTube; Greg Badros, former VP Engineering and Product at Facebook; and Esther Dyson (EdVenture), among others.

At launch, the app was designed to encourage healthier eating patterns without parents actually being able to see the child’s food diary. Instead, parents set a reward that was doled out simply for the child’s participation. That is, the parents couldn’t see what the child ate, specifically, which allowed them to stop playing “food police.”

ProfileStreak Phone

Unlike adult-oriented apps like MyFitnessPal or Noom, kids wouldn’t see metrics like calories, sugars, carbs and fat, but instead had their food choices categorized as “red,” “yellow” and “green.” However, no foods were designated as “off limits,” as it instead encouraged fewer reds and more greens.

The program also included an option for virtual coaching.

As a WW product, the program has remained somewhat the same. There are still the color-coded food categorizations and optional live coaching, via a subscription. Parents are still involved, now with updates after coaching calls or the option to join coaching sessions. The app also now includes tools that teach meditation, recipe videos and games that focus on healthy lifestyles. Subscribers gain access to one-on-one 15-minute virtual sessions with coaches whose professional backgrounds include counseling, fitness and other nutrition-related fields.

However, there are also things like a place to track measurements, goals like “lose weight” and Snapchat-style “tracking streaks.”

Home Tracked Phone

While the original program was designed to be a solution for parents with children who would have otherwise had to seek expensive medical help for obesity issues, the association with parent company and acquirer WW has led to some backlash.

CoachingChat Phone

Today, body positivity and fat acceptance movements have gone mainstream, encouraging people to be confident in their own bodies and not hate themselves for being overweight. The general thinking is that when people respect themselves, they become more likely to care for themselves — and this will extend to making healthier food and lifestyle choices.

Meanwhile, food tracking and dieting programs often lead to failure and shame — especially when people start to think of some food as “bad” or a “cheat,” instead of just something to be eaten in moderation. And excessive tracking can even lead to disordered eating patterns for some people, studies have found.

In addition, WW has already been under fire for extending its weight loss program to teens 13-17 for free, and the launch of what’s seen as a “dieting app for kids” as part of WW’s broader family-focused agenda certainly isn’t helping the backlash.

That said, when positive reinforcement is used correctly, it can work for weight loss. As TIME reported, the red-yellow-green traffic light approach was effective in adults in one independent study by Massachusetts General Hospital and another presented at the Biennial Childhood Obesity Conference worked in children, with 84% reducing their BMI after 21 weeks.

“According to recent reports from the World Health Organization, childhood obesity is one of the most serious public health challenges of the 21st century. This is a global public health crisis that needs to be addressed at scale,” said Joanna Strober, co-founder of Kurbo, in a statement about the launch. “As a mom whose son struggled with his weight at a young age, I can personally attest to the importance and significance of having a solution like Kurbo by WW, which is inherently designed to be simple, fun and effective,” she said.

KURBO.

I thought that I hated Weight Watchers. I have not hated them as much as I do right now.

Making weight loss trendy for children is making the development of eating disorders easier and trendier. I am not here for this.

— Anna Sweeney MS, CEDRD-S (@DietitianAnna) August 13, 2019

That said, it’s one thing for a parent to work in conjunction with a doctor to help a child with a health issue, but parents who foist a food tracking app on their kids may not get the same results. In fact, they may even cause the child to develop eating disorders that weren’t present before. (And no, just because a child is overweight, that doesn’t necessarily mean they’re suffering from an “eating disorder.”)

Weight Watchers has a new dieting app for kids as young as 8 and it is truly disturbing https://t.co/GjPl4PHwSv pic.twitter.com/ZMkZmFr9X6

— Dr. Yasmin (@DoctorYasmin) August 14, 2019

There can be many other factors that could be causing a child’s unexpected weight gain, beyond just their interest in eating high-calorie foods. This includes health ailments, hormone or chemical imbalances, medication side effects, puberty and other growth spurts (which can’t always be determined through BMI changes, which are tracked in-app), genetics, and more.

Parents may also be part of the problem, by simply bringing unhealthy food into the house because it’s more affordable or because they aren’t aware of things like hidden sugars or how to avoid them. Or perhaps they’re putting money into a child’s school lunch account, without realizing the child is able to spend it on vending machine snacks, sodas or off-menu items like pizza and chips.

The child may also suffer from health problems like asthma or allergies that have become an underlying issue, making it more difficult for them to be active.

In other words, a program like this is something that parents should approach with caution. And it’s certainly one where the child’s doctor should be involved at every stage — including in determining whether or not an app is actually needed at all.

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Study: Seasons have little effect on dieting app reporting but the day of week does

 If you’ve gotten three apps and a Fitbit so you can get skinnier this year, don’t worry so much about summer beach season or holiday weight gain. Instead, worry about Thursday. Researchers at University of South Carolina found that self-reporting of food was integral to weight loss but that self-reporters often fell off, seemingly around the holidays. “A key question we wanted… Read More

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Allurion offers gastric bypass surgery in a pill

839d5334-f27c-4a55-97f6-8fab1fca8b7b Just swallow a pill and it expands into a balloon in your stomach so you don’t feel hungry. No gastric bypass, no surgery required. Sounds magical, but Boston-based Allurion has created the only non-invasive gastric balloon for obesity. Gastric balloons are nothing new, but you usually need anesthesia and a doctor to insert them. That makes the whole process expensive and prohibitive… Read More

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