Meatable
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In what could be a starting gun for the commercialization of the cell-based meat business, upstart cultivated meat company Higher Steaks said it has managed to produce samples of its first products — bacon strips and pork belly made in a lab from cellular material.
With the revelation, Higher Steaks, a bootstrapped Cambridge, U.K.-based company, leapfrogs into a competitive position with a number of far larger companies that have raised far more capital.
“There’s still a lot of work until it’s commercial,” said Higher Steaks chief executive Benjamina Bollag, “but the revelation of a pork belly product that’s made from 50% cultivated cells and a bacon product which contains 70% meat grown from a cell material in a laboratory is something of a milestone for the industry.”
The remaining ingredients in Higher Steaks bacon and pork belly are a mixture of plant base, proteins, fats and starches to bind the cellular material together. To achieve this first step on its road to commercialization, Higher Steaks tapped the expertise of an undisclosed chef to formulate the meat into an approximation of the pork belly and bacon.
Higher Steaks head of research and development, Ruth Helen Faram (left) and chief executive Benjamina Bollag (right) Image Credits: Higher Steaks (opens in a new window)
At this stage, the pilot was more to show what Higher Steaks can do rather than what the company will do, said Bollag.
“In the future it will be scaffolding,” said Bollag. “It’s more showing what our meat can do and what we’re working on. In the future it will be with scaffolding.”
A number of companies, including Tantti Laboratories, Matrix Meats and Prellis Biologics, make the kind of biomaterial nano-scale scaffolding that could be used as a frame on which to grow structures equivalent to the fibrous textures of muscle.
The commercial viability of products from companies like Higher Steaks, Memphis Meats, Aleph Farms, Meatable, Integriculture, Mosa Meat and Supermeat depends on more than just companies like Tantti and Matrix, but also on the ability of Thermo Fisher, Future Fields and Merck to bring down the cost of the cell cultures that are required to grow the animal cells.
In all, some 30 cell-based meat startups have launched globally since 2014, and they’re all looking for a slice of the $1.4 trillion meat market.
Meanwhile, demand for pork continues to rise even as supplies have been decimated by an outbreak of African Swine Fever that could have killed as much as 40% of China’s population of pigs in 2019.
“Our mission is to provide meat that is healthy and sustainable without the consumer making any sacrifices on taste,” said Bollag in a statement. “The production of the first ever cultivated bacon and pork belly is proof that new techniques can help meet overwhelming demand for pork products globally.”
Given the highly capitalized competitors that Higher Steaks faces off against, the company is looking for industry partners to help commercialize its technology.
To improve its competitive position, Higher Steaks recently hired Dr. James Clark, the former chief technology officer of PredictImmune.
“I was always quite intrigued by cultured meat production, a mix of both science and food production. In 2013 I watched the first cultured meat burger from Mark Post costing £250,000, cooked on the BBC,” said Clark. “I was approached about joining Higher Steaks earlier this year and was attracted to joining primarily by the science along with the ambition and energy of the Higher Steaks founder Benjamina Bollag . I believe Higher Steaks is a company with a technology to be disruptive in the cultured meat area and at my career stage I was looking for a challenge.”
Brought in to scale the cultivated meat process at Higher Steaks, Clark has led the development of biotech and pharma products at early-stage and publicly traded companies.
“The addition of Dr. James Clark to the team gives Higher Steaks a significant advantage,” said Dr. Ruth Helen Faram, head of R&D. “Cultivated pork belly and bacon have never been demonstrated before and Higher Steaks is the first to develop a prototype containing over 70% cultivated pork muscle, without the use of bovine serum.”
Consumers shouldn’t expect to see Higher Steaks’ pork belly on store shelves or in restaurants anytime soon, Bollag cautioned. “We’re still in the thousands of pounds per kilogram.”
The company does expect to have a larger tasting event later this year.
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Memphis Meats, a developer of technologies to manufacture meat, seafood and poultry from animal cells, has raised $161 million in financing from investors, including Softbank Group, Norwest and Temasek, the investment fund backed by the government of Singapore.
The investment brings the company’s total financing to $180 million. Previous investors include individual and institutional investors like Richard Branson, Bill Gates, Threshold Ventures, Cargill, Tyson Foods, Finistere, Future Ventures, Kimbal Musk, Fifty Years and CPT Capital.
Other companies, including Future Meat Technologies, Aleph Farms, Higher Steaks, Mosa Meat and Meatable, are pursuing meat grown from cell cultures as a replacement for animal husbandry, whose environmental impact is a large contributor to deforestation and climate change around the world.
Innovations in computational biology, bio-engineering and materials science are creating new opportunities for companies to develop and commercialize technologies that could replace traditional farming with new ways to produce foods that have a much lower carbon footprint and bring about an age of superabundance, according to investors.
The race is on to see who will be the first to market with a product.
“For the entire industry, an investment of this size strengthens confidence that this technology is here today rather than some far-off future endeavor. Once there is a “proof of concept” for cultivated meat — a commercially available product at a reasonable price point — this should accelerate interest and investment in the industry,” said Bruce Friedrich, the executive director of the Good Food Institute, in an email. “This is still an industry that has sprung up almost overnight and it’s important to keep a sense of perspective here. While the idea of cultivated meat has been percolating for close to a century, the very first prototype was only produced six years ago.”
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Meatable, the Dutch startup developing cruelty-free technologies for manufacturing cultured meat, is pivoting to pork production as a swine flu epidemic ravages one quarter of the world’s pork supply — and has raised $10 million in financing to support its new direction.
When the company unveiled its technology last year, it was one of several companies working on the production of meat derived from animal cells — a method of meat production that theoretically has a far smaller carbon emissions footprint and is better for the environment than traditional animal farming.
At the time, it was one of several companies — including Memphis Meats, Future Meat Technologies, Aleph Farms, HigherSteaks and many, many pursuing technologies — to bring cultured beef to market. Now, as pork prices rise globally, Meatable becomes one of the first companies to publicly shift gears and turn its attention to the other white meat.

That’s not the only way the company is setting itself apart from its peers in the market. Meatable is also an early claimant to a commercially viable, patented process for manufacturing meat cells without the need to kill an animal as a prerequisite for cell differentiation and growth.
Other companies have relied on fetal bovine serum or Chinese hamster ovaries to stimulate cell division and production, but Meatable says it has developed a process where it can sample tissue from an animal, revert that tissue to a pluripotent stem cell, then culture that cell sample into muscle and fat to produce the pork products that palates around the world crave.
“We know which DNA sequence is responsible for moving an early-stage cell to a muscle cell,” says Meatable chief executive Krijn De Nood.
To pursue its new path, the company has raised $7 million from a slew of angel and institutional investors and a $3 million grant from the European Commission . Angel investors include Taavet Hinrikus, the chief executive and co-founder of TransferWise, and Albert Wenger, a managing partner at the New York-based venture firm Union Square Ventures.
Meatable’s De Nood says that the new cash will be used to accelerate the development of its prototype. The small-scale bioreactor the company had initially targeted for development in 2021 will now be ready by 2020 and the company is hoping to have an industry-scale plant online manufacturing thousands of kilograms of meat by 2025, according to De Nood.
Industrial farming is responsible for between 14% and 18% of the greenhouse gas emissions linked to global climate change and Meatable argues that cultured (lab-grown) meat has the potential to use 96% less water and 99% less land than industrial farming. Powering facilities using renewable energy could further reduce emissions associated with meat production, according to Meatable.
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